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Neuroimaging in fragile X-associated tremor/ataxia syndrome. MRI T2W axial (A) reveals symmetric ovoid lesions in the middle cerebellar peduncle, along with prominent foliae suggestive of diffuse cerebellar atrophy. T2 FLAIR axial sections (B, C) show signal changes in the subcortical and white matter and splenium [arrow in (B)]. FLAIR sagittal section (D) shows anterior callosal and splenial hyperintensity.
