Figure 1. Kaplan–Meier Estimates of Event-free Survival, as Assessed by the Local Investigators.

The log‑rank test was stratified according to disease stage and lactate dehydrogenase level at randomization. In the intention‑to‑treat analysis of event‑free survival, there were 105 events (38 in the neoadjuvant–adjuvant group and 67 in the adjuvant‑only group). All events that occurred before the start of adjuvant therapy were assigned an event date of 84 days. Tick marks indicate censored data.