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. Author manuscript; available in PMC: 2023 Aug 9.
Published in final edited form as: Sci Signal. 2023 May 9;16(784):eade1274. doi: 10.1126/scisignal.ade1274

Fig. 3. . Deletion of Ptpn6 restores T cell development in OT2 TCR transgenic Themis−/− mice.

Fig. 3. .

(A) Phenotypic comparison of thymocytes (left) and splenocytes (right) from representative mice of the indicated genotype. Numbers indicate the percentage of cells within each gate. Plots are representative of four or more mice analyzed for each genotype. (B) Numbers of CD4 SP thymocytes (left) and CD4+ splenocytes (right) from mice of the indicated genotype. Data are means ± SD of thymocyte or splenocyte subset numbers and were analyzed by two-tailed, type 2, t test. ***P < 0.005, ****P < 0.001. All comparisons are to OT2+/+ controls.