Table 5. Results of the DSC and FDM Analysesa,b.
| formulation | pH 3.7 | pH 6.5 | ||||||
|---|---|---|---|---|---|---|---|---|
| T′g, °C | Tcr, °C | Teu, °C | Tc, °C | T′g, °C | Tcr, °C | Teu, °C | Tc, °C | |
| M | –31.1 | –34.5 (C) | –35.8 | –37.8 (C) | ||||
| –23.8 (H) | –29.7 (H) | |||||||
| S | –33.5 | –31.9 | –36.9 | –32.2 | ||||
| H | –17.3 | –14.6 | –17.7 | –14.9 | ||||
| M* | –31.3 | –34.2 (C) | –35.9 | –37.4 (C) | ||||
| –26.7 (H) | –28.4 (H) | |||||||
| S* | –33.4 | –32 | –37.0 | - | –32.1 | |||
| H* | –17.8 | –14.2 | X | |||||
| Bo | –18.9 | –7.8 | X | |||||
| Mo | –32.4 | –35.4 (C) | –7.9 | –28.2 | –35.6 | –37.9 (C) | –9.3 | –28.2 |
| –26.3 (H) | –28.7 (H) | |||||||
| –20.2 (H) | ||||||||
| So | –41.5 | –23.3 (H) | –8.3 | –33.1 | –38.2 | –27.8 (H) | –10.3 | –32.1 |
| Ho | –33.5 | –16.5 | –7.8 | –18.3 | X | |||
| –23.6 | ||||||||
| Bo* | –12.6 | X | ||||||
| –7.9 | ||||||||
| Mo* | –32.0 | –34.5 (C) | –11.8 | –29.2 | –28.6 | –37.9 (C) | –13.6 | –26.3 |
| –26.4 | –22.6 (H) | –8.3 | –28.6 (H) | –9.7 | ||||
| So* | –39.1 | –14.9 | –33.1 | –38.3 | –10.1 | –32.1 | ||
| –8.7 | ||||||||
| Ho* | –29.5 | –11.1 | –18.2 | X | ||||
| –23.4 | –8.4 | |||||||
| Bo5 | –9.8 | X | ||||||
| –8.6 | ||||||||
| 0.9 | ||||||||
| Bo10 | –10.1 | X | ||||||
| –8.3 | ||||||||
| –2.5 | ||||||||
| Bo30 | –11.6 | –8.0 | X | |||||
| –5.9 | ||||||||
a
T′g: glass transition temperature of the maximally freeze-concentrated solution, Tcr: crystallization temperature, Teu: eutectic melting temperature, Tc: collapse temperature as determined by FDM, C: cooling, H: heating.
b
The table entries marked with ‘X’ indicate that measurements were not performed at that pH for the formulation under exam.