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. 2023 Jul 31;120(32):e2307269120. doi: 10.1073/pnas.2307269120

Table 1.

The metabolic phenotypes-associated SNPs and SLC25A47 gene expression in the liver of human

EA NEA 1000G Allele Frequencies GTEx Association
SNPs AFR (%) AMR (%) EAS (%) EUR (%) SAS (%) β* SE P-Value
rs1535464 A G 7 12 12 21 16 −0.013 0.057 0.82
rs35097172 T C 7 12 12 21 16 −0.012 0.060 0.84
rs1951519 A C 48 16 24 25 19 0.004 0.054 0.95
rs3736952 T C 7 12 13 19 17 −0.012 0.057 0.83
rs8015259 C G 50 16 25 23 20 −0.038 0.055 0.49
rs34184867 G C 6 31 23 47 66 −0.025 0.048 0.60
rs35007880 T G 4 31 23 49 66 −0.030 0.048 0.53
rs3736951 T C 4 31 23 49 66 −0.030 0.048 0.53
rs7147511 T C 4 31 23 47 66 −0.032 0.048 0.51

EA, effect allele; NEA, nonEA. AFR, AMR, EAS, EUR, and SAS. SE standard error.

*β is the regression coefficient based on the EA. β > 0 and β < 0 indicate that the effect/mutant allele regulates increased and reduced gene expression, respectively.

The threshold of statistical significance for eQTLs analysis was P < 0.05.