Table 1.
EA | NEA | 1000G Allele Frequencies | GTEx Association | |||||||
---|---|---|---|---|---|---|---|---|---|---|
SNPs | AFR (%) | AMR (%) | EAS (%) | EUR (%) | SAS (%) | β* | SE | P-Value† | ||
rs1535464 | A | G | 7 | 12 | 12 | 21 | 16 | −0.013 | 0.057 | 0.82 |
rs35097172 | T | C | 7 | 12 | 12 | 21 | 16 | −0.012 | 0.060 | 0.84 |
rs1951519 | A | C | 48 | 16 | 24 | 25 | 19 | 0.004 | 0.054 | 0.95 |
rs3736952 | T | C | 7 | 12 | 13 | 19 | 17 | −0.012 | 0.057 | 0.83 |
rs8015259 | C | G | 50 | 16 | 25 | 23 | 20 | −0.038 | 0.055 | 0.49 |
rs34184867 | G | C | 6 | 31 | 23 | 47 | 66 | −0.025 | 0.048 | 0.60 |
rs35007880 | T | G | 4 | 31 | 23 | 49 | 66 | −0.030 | 0.048 | 0.53 |
rs3736951 | T | C | 4 | 31 | 23 | 49 | 66 | −0.030 | 0.048 | 0.53 |
rs7147511 | T | C | 4 | 31 | 23 | 47 | 66 | −0.032 | 0.048 | 0.51 |
EA, effect allele; NEA, nonEA. AFR, AMR, EAS, EUR, and SAS. SE standard error.
*β is the regression coefficient based on the EA. β > 0 and β < 0 indicate that the effect/mutant allele regulates increased and reduced gene expression, respectively.
†The threshold of statistical significance for eQTLs analysis was P < 0.05.