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. 2023 Jul 31;120(32):e2309967120. doi: 10.1073/pnas.2309967120

Fig. 2.

Fig. 2.

Activin E regulates glycemic control and liver lipid content in mice. (A–D) Liver weights and lipid content. Fasted liver weight (A) and hepatic triglyceride content (B) in Control AAV or Inhbe AAV-treated mice on HFD (n = 9 to 10). Nonfasted liver weight (C) and hepatic triglyceride content (D) in Control AAV or Inhbe AAV-treated mice on HFD (n = 9 to 10). (E) Fasting plasma insulin levels before (baseline) and 3 wk after Inhbe AAV administration on chow (n = 9). (F and G) Glycemic control in Inhbe overexpressing mice. Oral glucose tolerance (F) and insulin tolerance tests (G) in mice administered with Control AAV or Inhbe AAV and fed chow or high-fat diets (n = 10). Mean ± SEM are shown in all graphs. **P < 0.01, ***P < 0.001.