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. 2023 Jun 26;11(6):e006166. doi: 10.1136/jitc-2022-006166

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© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.

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GM-Exo downregulate the STAT3 activity in M-MDSC. (A–D) Signaling proteins were analyzed by IB analysis (n=3). (E) Optical density values of proteins. (F) IB analysis of p-STAT3 and STAT3 in M-MDSCs (n=3). (G) Representative result of p-STAT3 MFI value in M-MDSC (n=3). (H) Summary graphs of p-STAT3 MFI values (n=3). tatistical analyses were performed using unpaired t-tests. M-MDSCs, monocytic myeloid-derived suppressor cells. (***p<0.001, one-way ANOVA test; error bars, SD). MFI, mean fluorescence intensity; PBS, phosphate buffer saline; GAPDH, glyceraldehyde-3-phosphate dehydrogenase