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. 2023 Aug 9;23:545. doi: 10.1186/s12903-023-03258-7

Table 5.

Frequency and nature of post-operative complications depending on the oral care of patients on biologics or immunosuppressants

All practitioners Specialized dentist activityc General dentist activity P-value All practitioners Specialized dentist activityc General dentist activity P-value
In patients under biologicsa In patients under immunosuppressantsb
N = 104 (%) N = 47 (%) N = 57 (%) N = 103 (%) N = 47 (%) N = 56 (%)
Postoperative complications occurring after dental invasive procedures
 No 91 (87.50) 37 (78.72) 54 (94.74) 84 (81.55) 33 (70.21) 51 (91.07)
 Yes 13 (12.50) 10 (21.28) 3 (5.26) 0.01 19 (18.45) 14 (29.79) 5 (8.93) 0.007
  Endodontic procedures 0 (0.00) 0 (0.00) 0 (0.00) - 0 (0.00) 0 (0.00) 0 (0.00) -
  Scaling and root planing 0 (0.00) 0 (0.00) 0 (0.00) - 0 (0.00) 0 (0.00) 0 (0.00) -
  Procedures requiring mucoperiosteal flap rising with bone cutting/curetting 5 (4.81) 5 (10.64) 0 (0.00) 0.01 6 (5.83) 5 (10.64) 1 (1.79) 0.05
  Soft-tissue surgery 1 (0.96) 1 (2.13) 0 (0.00) 0.26 0 (0.00) 0 (0.00) 0 (0.00) -
  Dental extraction(s) 13 (12.50) 10 (21.28) 3 (5.26) 0.01 19 (18.45) 14 (29.79) 5 (8.93) 0.007
  Implant(s) placement 2 (1.92) 2 (4.26) 0 (0.00) 0.11 2 (1.94) 2 (4.26) 0 (0.00) 0.11
Type of postoperative complications after invasive dental procedures
 Abscesses 2 (1.92) 2 (4.26) 0 (0.00) 0.11 3 (2.91) 2 (4.26) 1 (1.79) 0.45
 Cellulitis 2 (1.92) 2 (4.26) 0 (0.00) 0.11 3 (2.91) 1 (2.13) 2 (3.57) 0.66
 Dry socket 10 (9.62) 7 (14.89) 3 (5.26) 0.09 12 (11.65) 10 (21.28) 2 (3.57) 0.005
 Osteitis 4 (3.85) 2 (4.26) 2 (3.51) 0.84 3 (2.91) 2 (4.26) 1 (1.79) 0.45
 Delayed mucosal healing 12 (11.54) 10 (21.28) 2 (3.51) 0.005 15 (14.56) 12 (25.53) 3 (5.36) 0.004
 Implant(s) osseointegration failure 0 (0.00) 0 (0.00) 0 (0.00) - 1 (0.97) 1 (2.13) 0 (0.00) 0.27
 Jaw-bone osteonecrosis 5 (4.81) 4 (8.51) 1 (1.75) 0.10 1 (0.97) 1 (2.13) 0 (0.00) 0.27

aOnly practitioners who responded that they are concerned about the care of patients taking biologics (n = 104) were included in this analysis

bOnly practitioners who responded that they were concerned about the care of patients taking immunosuppressants (n = 103) were included in this analysis

cSpecialized dentist activity: oral surgery, periodontology, endodontics, pediatric dentistry