Table III.

Comparison of baseline parameters between SH-T1 patients who develop OH and with persistent SH at the end of follow-up

Parameter	OH (n= 6) Mean ±SD (range)	Persistent SH (n= 31) Mean ±SD (range)	p-value (* significance)
Age (years)	8.5 ±1.6 (6.1–9.7)	9.4 ±3.2 (3.3–14.5)	0.52
Sex (F), n(%)	4 (66.7)	17 (54.8)	0.48
TSH (µlU/ml) baseline	11.6 ±3.8 (7.5–17.7)	6.4 ±2.6 (4.4–13.1)	0.002*
fT4 (µlU/ml) baseline	0.0±0.1 (0.9–1.0)	1.2 ±0.2 (0.8–1.7)	0.15
BMI Z-score baseline	1.2 ±0.7 (0.0–2.0)	–0.1 ±1.4 (from –0.3 to 1.9)	0.03*
ΔBMI Z-score	–0.1 ±0.4 (from –0.8 to 0.3)	0.2 ±0.9 (from –2.2 to 2.1)	0.47
hSDS baseline	0.3 ±0.7 (from –1.0 to 1.0)	0.0 ±1.5 (from –2.9 to 4.3)	0.59
ΔhSDS	0.2 ±0.5 (from –0.3 to 0.7)	0.1 ±1.9 (from –2.2 to 2.9)	0.73
Abs (+), n(%)	1 (16.7)	11 (35.5)	0.10

SH – subclinical hypothyroidism; OH – patients with overt hypothyroidism; F – female sex; N – number; SD – standard deviation’ FU – follow-up; TSH – thyroid-stimulating hormone, fT4 – free thyroxine; hSDS – height standard deviation score; BMI – body mass index; Abs – antithyroid autoantibodie