Recommended dosage for older adults | 8 mg [25] |
Indications | Sleep onset insomnia [25, 26••] |
Contraindications | History of angioedema while taking ramelteon; use of fluvoxamine [28, 29] |
Main drug interactions | Fluvoxamine; rifampin; ketoconazole; fluconazole; donepezil; doxepin; alcohol [29] |
Main side effects | Occurred in ≥ 3% and more frequently than in those treated with placebo: somnolence, dizziness, fatigue, nausea, and exacerbated insomnia [29] |