Table 5.
Probability of remaining in advanced chronic kidney disease stages (4 and 5) based on various electronic health record phenotypes at the 6-month follow-up.
| Characteristic | Initial cohort (ICD=10a codes or eGFRb ≤30) (N=1759) | ICD-10 code N18.4 or N18.5 (n=1102) | Index eGFRc <30 (n=1391) | Index eGFR <30 and 90 days prior eGFR <60 (n=1346) | High risk (n=928) | Intermediate risk (n=480) | Low risk (n=315) | |||||||||
|
|
Value | 95% CI | Value | 95% CI | Value | 95% CI | Value | 95% CI | Value | 95% CI | Value | 95% CI | Value | 95% CI | ||
| eGFR, mean (SD) | 26.2 (12.1) | 26-27 | 27.7 (13.7) | 27-29 | 22.0 (6.5) | 22-22 | 22.0 (6.5) | 22-22 | 20.3 (6.6) | 20-21 | 27.4 (5.6) | 27-28 | 42.1 (16.6) | 40- 44 | ||
| Days between stage-defining eGFR values, mean (SD) | 263.8 (394.3) | 245-282 | 229.0 (304.9) | 211- 247 | 274.3 (399.8) | 253-296 | 260.7 (341.7) | 242-279 | 226.7 (159.3) | 216-237 | 316.0 (526.0) | 269-363 | 296.8 (594.2) | 231-363 | ||
| Subsequent eGFR measurement, n (%) | 981 (55.8) | 53%-58% | 706 (64.1) | 61%-67% | 753 (54.1) | 51%-57% | 751 (55.8) | 53%-58% | 549 (59.2) | 56%-62% | 238 (49.6) | 45%-54% | 180 (57.1) | 51%-63% | ||
| Any subsequent eGFR ≥30 after index eGFR, n (%) | 293 (16.7) | 15%-19% | 271 (24.6) | 22%-27% | 96 (6.9) | 5.7%-8.4% | 96 (7.1) | 5.8%-8.7% | 39 (4.2) | 3.0%-5.8% | 85 (17.7) | 14%-21% | 162 (51.4) | 46%-57% | ||
| Current eGFR ≥30 at 6-month follow-up, n (%) | 257 (26.2) | 23%-29% | 245 (34.7) | 31%-38% | 75 (10.0) | 8.0%-12.0% | 75 (10.0) | 8.0%-12.0% | 32 (5.8) | 4.1%-8.2% | 69 (29.0) | 23%-35% | 151 (83.9) | 78%-89% | ||
aICD-10: International Classification of Diseases, Tenth Revision.
beGFR: estimated glomerular filtration rate (ml·min–1·m–2).
cIndex eGFR: latest eGFR measure at the time of extraction of the cohort.