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. 2023 Jul 31;19(12):3869–3891. doi: 10.7150/ijbs.85467

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Role of tricarboxylic acid cycle-related cellular metabolites in AAD. The process of the intracellular tricarboxylic acid cycle and the role of the corresponding metabolites in AAD. The process figures those molecules and reactions found in the TCA cycle in mitochondria. Abbreviations: TCA cycle, tricarboxylic acid cycle; HSD, high salt diet; α-KG, alpha‑ketoglutarate; ACO2, aconitase-2; Acetyl-CoA, acetyl coenzyme A; OGDH, oxoglutarate dehydrogenase; ROS, reactive oxygen species; ETC, electron transport chain; IL-6, interleukin-6; IL-1β, interleukin-1β; MCP-1, monocyte chemoattractant protein 1; NR1D1, NR subfamily 1 group D member 1; CREB, cyclic adenosine monophosphate-responsive element-binding protein 1.