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. 2023 Jul 16;19(12):3709–3725. doi: 10.7150/ijbs.84577

Figure 6.

Figure 6

Human clinical study to link the AR/ circ-SLCO1B7/ miR-139-5p/ TPD52 signaling to the lung cancer progression. A.The expression level of circ-SLCO1B7 in our collected lung cancer tissues and the adjacent normal tissues. B. The correlation between circ-SLCO1B7 and AR of our collected lung cancer samples. C. The correlation between circ-SLCO1B7 and miR-139-5p of our collected lung cancer samples. D. The correlation between circ-SLCO1B7 and TPD52 of our collected lung cancer samples. E-F. Expression of miR-139-5p and TPD52 in normal (N) tissues and tumor (T) tissues according to the TCGA database. G-H. Expression of miR-139-5p in different grades (T1-4) and stages (Stage I-IV) of lung cancer. I. Expression of TPD52 in different grades (T1-4) of lung cancer. J. Correlation analysis of AR and miR-139-5p expression. K. Correlation analysis of miR-139-5p and TPD52 expression. L. Correlation analysis of AR and TPD52 expression. All quantitations are presented as mean ± SD, and p-values were calculated using the t-test. Significance levels are denoted as *p < 0.05, **p < 0.01, and ***p < 0.001.