Table 1.
Baseline demographics and characteristics of patients.
| NASH (n = 38) | HBV (n = 82) | p value | |
|---|---|---|---|
| Age | 56.7 ± 8.8 | 49.2 ± 9.4 | <0.001 |
| Female | 21 (55.3) | 17 (20.7) | <0.001 |
| BMI (kg/m2) | 24.7 ± 4.1 | 21.7 ± 2.6 | 0.032 |
| Overweight/Obese | 18 (47.4) | 9 (11.0) | <0.001 |
| Ascites | 0.319 | ||
| Mild | 15 (39.5) | 33 (40.2) | |
| Moderate/Excessive | 4 (10.5) | 17 (20.7) | |
| Metabolic syndrome | 19 (50.0) | 6 (7.3) | <0.001 |
| Esophageal varices | 34 (89.5) | 77 (93.9) | 0.392 |
| Gastric varices | 30 (78.9) | 66 (80.5) | 0.844 |
| Hypertension | 8 (21.0) | 5 (6.1) | 0.014 |
| Diabetes | 28 (73.7) | 27 (32.9) | <0.001 |
| Hypertriglyceridemia | 10 (26.3) | 0 | <0.001 |
| Child–Pugh score | 6.7 ± 1.5 | 7.2 ± 1.7 | 0.097 |
| Child–Pugh class | 0.124 | ||
| Child class A | 22 (57.9) | 33 (40.2) | |
| Child class B | 15 (39.5) | 40 (48.9) | |
| Child class C | 1 (2.6) | 9 (11.0) | |
| MELD | 10.5 ± 2.4 | 11.8 ± 3.2 | 0.034 |
| Platelets (×109/L) | 83.5 ± 41.2 | 67.0 ± 49.7 | 0.003 |
| Albumin (g/dL) | 3.4 ± 0.6 | 3.3 ± 0.6 | 0.520 |
| Bilirubin (mg/dL) | 1.4 ± 0.9 | 1.6 ± 1.3 | 0.254 |
| ALT (U/L) | 27.4 ± 17.8 | 42.3 ± 55.8 | 0.031 |
| AST (U/L) | 38.1 ± 27.9 | 42.5 ± 41.1 | 0.492 |
| GGT (U/L) | 64.2 ± 71.4 | 43.4 ± 35.4 | 0.034 |
| AP (U/L) | 92.7 ± 56.6 | 80.5 ± 28.3 | 0.118 |
| INR | 1.3 ± 0.2 | 1.4 ± 0.3 | 0.004 |
| Serum creatinine (mg/dL) | 0.8 ± 0.2 | 0.7 ± 0.2 | 0.602 |
| Serum sodium (mmol/L) | 138.9 ± 3.6 | 138.0 ± 4.3 | 0.247 |
| Portal vein diameter (mm) | 15.6 ± 3.1 | 16.8 ± 3.3 | 0.030 |
BMI, body mass index; HCC, hepatocellular carcinoma; MELD, model of end-stage liver disease score; ALT, alanine aminotransferase; AST, aspartate aminotransferase; GGT, gamma-glutamyl transpeptidase; AP, alkaline phosphatase; INR, international normalized ratio.