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. 2023 Jul 25;14:1165939. doi: 10.3389/fphys.2023.1165939

TABLE 5.

Changes in the relative changes from the baseline cerebral metabolic rate for oxygen and cerebral blood volume in response to 17-min low-intensity cycling ergometer exercises, followed by 3-min moderate-intensity cycling ergometer exercises.

Ex3 Ex13 Ex20 Post1 Post2 Post3 Post15 ES (η2-partial)
rCMRO2
 Rt 1.04 ± 0.08 1.14 ± 0.13 1.24 ± 0.20**, § 1.20 ± 0.15** 1.21 ± 0.19** 1.13 ± 0.16 1.07 ± 0.18 0.466
 Lt 1.05 ± 0.05 1.09 ± 0.09 1.16 ± 0.10** 1.18 ± 0.11**, § 1.14 ± 0.13* 1.08 ± 0.11 1.05 ± 0.11 0.406
rCBV
 Rt 1.00 ± 0.02 1.04 ± 0.04** 1.07 ± 0.05**, § 1.07 ± 0.04** 1.07 ± 0.05**, § 1.05 ± 0.04** 1.01 ± 0.05 0.633
 Lt 1.00 ± 0.02 1.03 ± 0.04 1.06 ± 0.05** 1.07 ± 0.05**, § 1.06 ± 0.05* 1.05 ± 0.04 1.01 ± 0.04 0.406
rCBF
 Rt 1.01 ± 0.07 1.15 ± 0.14** 1.28 ± 0.22**, § 1.26 ± 0.18** 1.28 ± 0.22**, § 1.21 ± 0.16** 1.06 ± 0.20 0.631
 Lt 0.99 ± 0.04 1.11 ± 0.12** 1.20 ± 0.15** 1.23 ± 0.15**, § 1.20 ± 0.16**, § 1.18 ± 0.14** 1.02 ± 0.13, § 0.641
rOEF
 Rt 1.04 ± 0.04 0.99 ± 0.05 0.98 ± 0.07*, § 0.96 ± 0.06** 0.95 ± 0.05** 0.93 ± 0.04**, § 1.02 ± 0.05 0.456
 Lt 1.06 ± 0.04 0.99 ± 0.05** 0.98 ± 0.07**, § 0.97 ± 0.07** 0.95 ± 0.04** 0.93 ± 0.07**, § 1.04 ± 0.04, § 0.608

Values are expressed as the mean ± standard deviation (n = 12) at 3 min (Ex3), 13 min (Ex13), and 20 min (Ex20) after exercise initiation and 1 min (Post1), 2 min (Post2), 3 min (Post3), and 15 min (Post15) after exercise termination.

The data were averaged over 15 s for each time point.

rCMRO2: relative changes from the baseline in the cerebral metabolic rate for oxygen; rCBV: the relative changes from the baseline in the cerebral blood volume; rCBF: the relative changes from the baseline in cerebral blood flow; rOEF: the relative changes from the baseline in oxygen extract fraction; Rt: right; Lt: left.

Significance of difference from Ex 3: *p < 0.05 and **p < 0.001. Significance of difference from Ex13: §p < 0.05.

ES: effect size.

rCMRO2, rCBV, rCBF, and rOEF are demonstrated when ScO2 or [HbT] changed significantly from the baseline.