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. 2023 Jul 24;14:1004245. doi: 10.3389/fendo.2023.1004245

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Copyright © 2023 Liu, Wei, Wang, Liu, Zhang, Liu, Liu and Ye

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Analysis of differentially expressed genes and master regulators of 40-49 vs. 30-39. (A) Volcano plot of differentially expressed genes. (B) GSEA analysis (log2FC ranking), signaling pathways enriched in the 30-39 age group. (C) GSEA analysis, signaling pathways enriched in the 40-49 age group. (D) Mapping of signaling pathways enriched in the two subgroups to single-cell sequencing data. (E) Results of master regulator analysis.