Table 2. Snakes species with neurotoxic (Postsynaptic) effects in humans [23, 24].
Species | Habitat/habit | Other toxins | Clinical manifestation | Antivenom availability |
---|---|---|---|---|
Forest Cobra (Naja melanoleuca)** | Forest, around inhabited areas and near water | Cardiotoxins | Ptosis, cranial nerve palsies, bulbar and respiratory paralysis (moderate to severe flaccid paralysis). Local effects: pain, severe swelling, bruising, blistering, necrosis | FAV-Afrique, SAIMR Polyvalent Antivenom, Antivipmyn Africa, Bivalent Naja / Walterinnesia Snake Antivenom, SAIMR Snakebite Kit |
Black-necked spitting cobra (Naja nigricollis)* | Moist savanna and Nocturnal |
Necrotoxins+, Cardiotoxins |
Flaccid paralysis, severe swelling, bruising, blistering, necrosis, venom spit ophthalmia: kerato-conjuctivitis, corneal ulceration | Bivalent Naja / Walterinnesia Snake Antivenom, Antivipmyn Africa, Pan-African antivenom (EchiTAb-Plus-ICP), Polyvalent Snake Venom Antiserum,FAV-Afrique, Favirept |
West African brown spitting cobra (Naja katiensis)* | Savanna, Diurnal, & arboreal | Cardiotoxins | Moderate to severe flaccid paralysis Severe swelling, bruising, blistering and necrosis Venom spit ophthalmia: kerato-conjuctivitis, corneal ulceration |
Bivalent Naja / Walterinnesia Snake Antivenom, Antivipmyn Africa |
Senegalese cobra (Naja senegalensis)* | Savanna, riparian forests | Myotoxins+ Cardiotoxins Necrotoxins+ |
Moderate to severe flaccid paralysis Severe swelling, bruising, blistering and necrosis |
FAV-Afrique |
Gold’s tree cobra (Pseudohaje goldii)** | Forest, woodland, near watercourses, Arboreal & diurnal | unknown | Insufficient data | None presently |
Black Tree Cobra (Pseudohaje nigra)** | Forest, woodland, near watercourses, Arboreal & diurnal | unknown | Insufficient data | None presently |
Western Green Mamba (Dendroaspis viridis)* | Forest, thicket and woodland, farms, Diurnal, arboreal | Dendrotoxins Fasciculins | Flaccid paralysis, neuroexcitation, increased sweating, salivation | FAV-Afrique, Antivipmyn Africa |
[+ = present but not defined
* = WHO category 1—Highest medically important venomous snakes
** = WHO category 2—Secondary medically important highly venomous snakes]