Table 4. Snake species with haemorrhagic (haematotoxic) manifestations in humans [23, 24].
Common name | Habitat/habit | Other toxins | Clinical manifestation | Antivenom availability |
---|---|---|---|---|
West African Carpet Viper (Echis ocellatus)** | Terrestrial, nocturnal and crepuscular | Anticoagulants, Nephrotoxins, Mixture of procoagulants, Necrotoxins, | Renal complication, secondary to coagulopathy, Marked local effects (pain, severe swelling, bruising, blistering), Moderate to severe necrosis | SAIMR Echis Antivenom, FAV-Afrique, Pan-African antivenom (EchiTAb-Plus-ICP), EchiTAbG, Antivipmyn Africa, SAIMR Echis antivenom |
West African Green Tree Viper (Atheris chloroechis)* | Forest, semi-arid areas, Diurnal and arboreal | Severe envenoming possible, potentially lethal, Local pain, swelling, bruising & blistering, Coagulopathy & hemorrhages are uncommon to rare, but may be moderate to severe coagulopathy | No Antivenoms | |
Puff adder (Bitis arietans)* | Savanna, nocturnal | Procoagulants Anticoagulants Nephrotoxins Necrotoxins+ |
Marked local effects; pain, severe swelling, bruising, blistering, Moderate to severe local Necrosis, Common, moderate to severe coagulopathy + haemorrhagins causing extensive bleeding, Cardiotoxicity is common and is major clinical effect, Shock secondary to fluid shifts due to local tissue injury is likely in severe cases | SAIMR Snakebite Kit, Antivipmyn Africa, Pan-African antivenom (EchiTAb-Plus-ICP), Polyvalent Snake Venom Antiserum, FAV-Afrique, Favirept, SAIMR Polyvalent Antivenom |
Gaboon Viper (Bitis rhinoceros)** | Forest, nocturnal |
Procoagulants, Fibrinogenases) Anticoagulants Cardiotoxins+ Necrotoxins+ |
Marked local effects; pain, severe swelling, bruising, blistering, Minor neurotoxic paralysis, Coagulopathy & Haemorrhages, very common, coagulopathy + haemorrhagins causing bleeding is major clinical effect, Cardiotoxicity common, | FAV-Afrique, Antivipmyn Africa, Polyvalent Snake Venom Antiserum SAIMR Polyvalent Antivenom SII Polyvalent |
Boomslang (Dispholidus typus*) | Open bush, savannah, wooded grassland, Diurnal and arboreal | Procoagulants Anticoagulants |
Local pain, swelling & bruising Coagulopathy & Haemorrhages Common, moderate to severe coagulopathy + haemorrhagins causing extensive bleeding |
SAIMR Boomslang Antivenom |
[+ = present but not defined
* = WHO category 1—Highest medically important venomous snakes
** = WHO category 2—Secondary medically important highly venomous snakes].