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. 2023 Jul 28;17(7):e0011050. doi: 10.1371/journal.pntd.0011050

Table 7. Anti-snake venom sera availability [2628].

S. No. Type of antivenom Manufacturer Country of origin Status of production currently Snake species Comment
1 FAV-Afrique Sanofi Pasteur France Discontinued in January 2014. Last batch expired in Jan 2016 10 species of the Elapidae and Viperidae families The most highly effective in treating envenoming by Echis ocellatus, the West African saw-scaled viper that causes great morbidity and mortality throughout the West and Central African savannah
MicroPharm Limited acquired product in 2018 and seeking to re-launch it
2 SAIMR Polyvalent Antivenom South African
Vaccine Producers
South Africa Active production B. arietans, B. gabonica, D. angusticeps, D. jamesoni, D. polylepis, H.
haemachatus, N. annulifera, N. melanoleuca, N. mossambica, N. nivea
Considered as the current “Gold Standard” for treating envenomings by many African snake species
3 Antivipmyn Africa Instituto Bioclon / Silanes Mexico Active production B. arietans,
B. gabonica, B. rhinoceros, D. angusticeps, D. jamesoni, D. polylepis, D. viridis,
E. leucogaster, E. ocellatus,
E. pyramidum, N. haje,
N. katiensis, N. melanoleuca, N. nigricollis, N. nivea
4 Bivalent Naja / Walterinnesia Snake Antivenom National Antivenom and Vaccine Production Centre Saudi Arabia Active production N. arabica
N. haje
N. melanoleuca
N. naja
N. nigricollis
N. nivea
Walterinnesia aegyptia
Walterinnesia morgani
5 Pan-African antivenom (EchiTAb-Plus-ICP) Instituto Clodomiro Picado (ICP)
University of Costa Rica
Costa Rica Active production B. arietans,
E. ocellatus,
N. nigricollis
D. polylepis)
N. mossambica
N. annulifera
H. haemachatus
Intact IgG
The expanded-scope EchiTAb + ICP has lower ability to neutralize the venom of B. arietans, but similar ability to neutralize the venoms of D. polylepis, N. mossambica and H. haemachatus
When compared to FAV Afrique and the SVA African antivenoms
6 Snake Venom Antiserum Bharat Serums & Vaccines India B. caeruleus
N. haje
7 Inoserp Pan-Africa Inosan Biopharma Mexico Active production E. ocellatus,
E. leucogaster, E. pyramidum, B. arietans,
B. rhinoceros,
B. nasicornis,
B. gabonica
D. polylepis,
D. viridis,
D. angusticeps, D. jamesoni,
N. nigricollis,
N. melanoleuca, N. haje,
N. pallida
N. nubiae,
N. katiensis N. senegalensis.
Lyophilized
Polyvalent F(ab’)2 Immunoglobulin Fragments (Equine)
8 Favirept Polyvalent Snake Antivenin Sanofi Pasteur France Discontinued B. arietans
C. cerastes
D. deserti
E. leucogaster
N. nigricollis,
N. melanoleuca, N. haje,
9 SII Polyvalent Antisnake
(Snake Antivenom Seum IP)
Serum Institute of India India Active production N. naja
E. carinatus
D. russelii
B. caeruleus
Polyvalent equine antivenom
10 SAIMR Echis Antivenom South African
Vaccine Producers
South Africa Active production E. carinatus,
E. ocellatus,
E. coloratus, Cerastes spp.
11 EchiTAbG MicroPharm United Kingdom Active production Echis ocellatus
12 SAIMR Boomslang Antivenom South African
Vaccine Producers
South Africa Active production Dispholidus typus
13 Snake Venom Antiserum (African)
(AFRIVEN-10)
VINS Bioproducts India In active production B. arietans,
B. gabonica,
E. ocellatus,
E. leucogaster, N. haje,
N. melanoleuca, N. nigricollis,
D. polylepis,
D. viridis,
D. jamesoni.
Lyophilized powder
Polyvalent, enzyme-refined equine antivenom immunoglobulin fragments
14 Snake Venom Antiserum (Pan African)
(PANAF-Premium)
Premium Serums and Vaccines India In active production B. arietans,
B. gabonica,
B. nasicornis,
B. rhinoceros
D. angusticeps, D. jamesoni,
D. polylepis,
D. viridis,
E. carinatus,
E. leucogaster, E. ocellatus,
N. nigricollis,
N. haje,
N. melanoleuca
Lyophilized powder
Polyvalent, enzyme-refined equine antivenom immunoglobulins
15 Anti-Snake Venom Serum Pan Africa [10]
BEAFRIQUE-10
M/s. Biological E India In active production B. arietans,
B. gabonica,
E. ocellatus,
E. leucogaster, N. haje,
N. melanoleuca, N. nigricollis,
D. polylepis,
D. viridis,
D. jamesoni.
Liquid,
Polyvalent, Enzyme refined, Equine F(ab’) immunoglobulin