Table 4. Summary of binary and continuous pre-transplant variables, outcome variables.
For continuous variables, we include the mean and standard deviation for the overall dataset and clusters. For binary variables, we include the count.
| All (n = 187) | N1 (n = 83) | N2 (n = 82) | N3 (n = 22) | p-value | |
|---|---|---|---|---|---|
| Pre-transplant Features | |||||
| Donor age | 33.47 ± 8.27 | 32.82 ± 9.27 | 31.61 ± 8.55 | 31.70 ± 6.83 | 0.22 |
| Recipient age | 9.93 ± 5.31 | 5.61 ± 2.71 | 14.19 ± 3.79 | 10.35 ± 4.54 | <0.001 |
| CD34+ cell doses per kilogram (10⌃6/kg) | 11.89 ± 9.91 | 15.03 ± 10.44 | 8.53 ± 7.53 | 12.56 ± 11.94 | <0.001 |
| CD3+ cell doses per kilogram (10⌃6/kg) | 4.74 ± 3.86 | 6.11 ± 4.50 | 3.15 ± 2.75 | 4.43 ± 2.87 | <0.001 |
| CD3+ cell to CD34+ cell ratio | 5.39 ± 9.60 | 5.16 ± 11.17 | 5.61 ± 8.80 | 4.16 ± 3.69 | 0.81 |
| Recipient stem cell body mass (kg) | 35.81 ± 19.65 | 20.83 ± 9.14 | 50.27 ± 18.01 | 35.08 ± 15.02 | <0.001 |
| Donor age below 35 | 104 (55.61%) | 48 (57.83%) | 40 (48.78%) | 16 (72.73%) | 0.115 |
| Presence of cytomegalovirus infection (CMV) in donor prior to transplantation | 72 (38.50%) | 33 (39.76%) | 30 (36.59%) | 9 (69.23%) | 0.889 |
| Recipient age below 10 | 99 (52.94%) | 83 (100%) | 7 (8.54%) | 9 (40.91%) | 0.001 |
| Recipient gender | 112 males (65.24%) | 46 (55.42%) | 52 (63.41%) | 14 (63.64%) | 0.537 |
| Presence of CMV in recipient prior to transplantation | 100 (53.48%) | 42 (50.60%) | 44 (53.66%) | 14 (63.64%) | 0.552 |
| Disease categorized as malignant | 155 (82.89%) | 62 (74.70%) | 75 (91.46%) | 18 (81.82%) | 0.017 |
| Compatibility of donor and recipient according to gender (incidence of female to male) | 32 (17.11%) | 11 (13.25%) | 16 (19.51%) | 5 (22.73%) | 0.429 |
| Compatibility of donor and recipient according to blood group (incidence of matched) | 52 (27.81%) | 21 (25.30%) | 26 (31.71%) | 6 (27.27%) | 0.655 |
| Incidence of HLA match | 159 (85.03%) | 82 (98.80%) | 62 (75.61%) | 15 (68.18%) | <0.001 |
| Risk Group (high, low) | 69 high risk (36.90%) | 26 (31.33%) | 34 (41.47%) | 9 (40.91%) | 0.369 |
| Stem cells source (peripheral, bone marrow) | 145 peripheral (77.54%) | 67 (80.72%) | 60 (73.17%) | 18 (81.82%) | 0.446 |
| Outcomes | |||||
| 1-year Survival Time (Days) | 286 ± 132.39 | 312.11 ± 116.25 | 259.02 ± 143.87 | 291.72 ± 130.60 | 0.035 |
| 1-year Survival Rate | 64.71% | 74.39% | 54.88% | 68.18% | 0.041 |
| Study Duration Survival Rate | 54.54% | 61.45% | 43.90% | 68.18% | 0.03 |