表表 1 急性痛风性关节炎(AGA)患者与健康志愿者血清中50种蛋白质的表达差异
|
编号 |
蛋白质名称 |
AGA组 |
健康对照组 |
Log 2差异倍数 |
P值 |
|
1 |
IL-8 |
2.65 |
0.97 |
1.68 |
0.00 |
|
2 |
TNF RⅡ |
12.53 |
12.04 |
0.49 |
0.00 |
|
3 |
TIMP-2 |
13.27 |
13.07 |
0.19 |
0.00 |
|
4 |
MIP-1β |
5.96 |
4.61 |
1.35 |
0.00 |
|
5 |
GM-CSF |
0.16 |
1.34 |
-1.18 |
0.00 |
|
6 |
IL-6 R |
10.74 |
10.58 |
0.15 |
0.01 |
|
7 |
TNF RI |
12.98 |
12.59 |
0.39 |
0.01 |
|
8 |
B7-H1 |
1.75 |
4.52 |
-2.77 |
0.02 |
|
9 |
PD-L2 |
1.34 |
4.87 |
-3.53 |
0.03 |
|
10 |
IL-4 |
0.11 |
1.72 |
-1.62 |
0.02 |
|
11 |
PDGF-BB |
13.23 |
13.05 |
0.17 |
0.03 |
|
12 |
RANTES |
11.21 |
11.09 |
0.12 |
0.03 |
|
13 |
IL-7 |
1.52 |
2.36 |
-0.84 |
0.06 |
|
14 |
ICOS |
6.59 |
8.99 |
-2.40 |
0.10 |
|
15 |
PD-L1 |
2.77 |
4.46 |
-1.69 |
0.12 |
|
16 |
Eotaxin-2 |
7.17 |
7.63 |
-0.46 |
0.14 |
|
17 |
IFNG |
0.83 |
1.78 |
-0.95 |
0.15 |
|
18 |
IL-1ra |
6.70 |
6.09 |
0.61 |
0.14 |
|
19 |
IL-5 |
0.91 |
2.15 |
-1.23 |
0.14 |
|
20 |
MIP-1α |
8.30 |
7.69 |
0.61 |
0.15 |
|
21 |
TNFα |
0.68 |
2.15 |
-1.47 |
0.12 |
|
22 |
IL-12 p70 |
0.02 |
0.29 |
-0.27 |
0.16 |
|
23 |
CTLA-4 |
4.75 |
6.20 |
-1.45 |
0.19 |
|
24 |
GCSF |
4.31 |
5.45 |
-1.14 |
0.20 |
|
25 |
IL-16 |
5.84 |
5.08 |
0.76 |
0.20 |
|
26 |
MIG |
6.64 |
5.63 |
1.01 |
0.18 |
|
27 |
TIMP-1 |
11.78 |
11.66 |
0.12 |
0.19 |
|
28 |
IL-13 |
0.15 |
0.71 |
-0.56 |
0.24 |
|
29 |
MIP-1δ |
10.57 |
10.70 |
-0.13 |
0.24 |
|
30 |
TNFβ |
0.56 |
1.99 |
-1.43 |
0.23 |
|
31 |
I-309 |
2.44 |
3.31 |
-0.87 |
0.26 |
|
32 |
BLC |
4.68 |
4.28 |
0.40 |
0.29 |
|
33 |
B7-H2 |
10.83 |
10.41 |
0.43 |
0.34 |
|
34 |
IL-12 p40 |
6.27 |
5.86 |
0.40 |
0.35 |
|
35 |
MCP-1 |
6.34 |
6.63 |
-0.29 |
0.39 |
|
36 |
IL-2 |
2.26 |
3.25 |
-0.99 |
0.44 |
|
37 |
B7-H3 |
8.35 |
8.66 |
-0.31 |
0.53 |
|
38 |
IL-1α |
8.00 |
8.08 |
-0.07 |
0.54 |
|
39 |
PD-1 |
8.26 |
8.63 |
-0.38 |
0.60 |
|
40 |
ICAM-1 |
13.55 |
13.50 |
0.05 |
0.59 |
|
41 |
IL-11 |
1.03 |
1.57 |
-0.54 |
0.59 |
|
42 |
Eotaxin |
6.68 |
6.81 |
-0.13 |
0.67 |
|
43 |
IL-6 |
1.99 |
1.71 |
0.29 |
0.65 |
|
44 |
IL-15 |
1.72 |
2.03 |
-0.31 |
0.67 |
|
45 |
IL-10 |
1.37 |
1.26 |
0.10 |
0.69 |
|
46 |
IL-17 |
1.39 |
1.21 |
0.17 |
0.80 |
|
47 |
B7-2 |
7.81 |
7.98 |
-0.17 |
0.83 |
|
48 |
CD28 |
4.33 |
4.16 |
0.17 |
0.91 |
|
49 |
IL-1β |
2.84 |
2.80 |
0.04 |
0.95 |
|
50 |
M-CSF |
0.00 |
0.00 |
0.00 |
0.00 |