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. 2023 Jul 27;55(8):1301–1310. doi: 10.1038/s41588-023-01446-3

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 7 — a, ROC curves for detection of lung cancer in the high-risk LUCAS cohort using GEMINI or the combined GEMINI / DELFI approach in patients with stages II-IV disease and in the subset of these patients that smoked ≥40 pack years. b, ROC curves for detection of lung cancer in the high-risk LUCAS cohort using GEMINI or the combined GEMINI / DELFI approach in patients with adenocarcinoma, squamous cell carcinoma, or small cell lung cancer and in the subset of these patients that smoked ≥40 pack years. Performance for Stage I disease is shown in Fig. 4f. AUC, area under the curve; CI, confidence interval.