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. 2023 Aug 9;13:12933. doi: 10.1038/s41598-023-39641-1

Table 1.

Baseline characteristics of participants based on NAFLD stratification.

Characteristic NAFLD p-value
No Yes
N 3056 2361
Demographics
 Age (year), mean ± SD 47.84 ± 18.12 51.06 ± 15.97 < 0.001
Sex
 Male 1318 (43.13%) 1133 (47.99%)
 Female 1738 (56.87%) 1228 (52.01%)
Race < 0.001
 Mexican American 342 (11.19%) 388 (16.43%)
 Other Hispanic 302 (9.88%) 263 (11.14%)
 Non-Hispanic White 1188 (38.87%) 1024 (43.37%)
 Non-Hispanic Black 613 (20.06%) 484 (20.50%)
 Other race—including multi-racial 611 (19.99%) 202 (8.56%)
Education level < 0.001
 < High school 555 (18.16%) 513 (21.73%)
 High school 613 (20.06%) 575 (24.35%)
 > High school 1888 (61.78%) 1273 (53.92%)
PIR < 0.001
 <  = 1 628 (20.55%) 549 (23.25%)
 1–3 1213 (39.69%) 1059 (44.85%)
 > 3 1215 (39.76%) 753 (31.89%)
Behavioral characteristics
 Smoking status < 0.001
  Never 1929 (63.12%) 1285 (54.43%)
  Now 488 (15.97%) 421 (17.83%)
  Former 639 (20.91%) 655 (27.74%)
 Work activities status 0.048
  No 1813 (59.33%) 1312 (55.57%)
  Moderate 662 (21.66%) 559 (23.68%)
  Vigorous 118 (3.86%) 94 (3.98%)
  Both 463 (15.15%) 396 (16.77%)
 Recreational activities status < 0.001
  No 1349 (44.14%) 1359 (57.56%)
  Moderate 858 (28.08%) 624 (26.43%)
  Vigorous 279 (9.13%) 122 (5.17%)
  Both 570 (18.65%) 256 (10.84%)
Dietary characteristics
 Dietary energy intake (kcal), Mean ± SD 3934.68 ± 1481.90 3989.11 ± 1616.94 0.198
 Dietary protein intake (mg), mean ± SD 156.71 ± 66.36 160.26 ± 70.70 0.058
 Dietary folate intake (mcg), median (Q1-Q3) 710.00 (500.00–985.25) 673.00 (476.00–928.00) 0.012
Related disease conditions
 Hypertension status < 0.001
  No 2084 (68.19%) 1053 (44.60%)
  Yes 972 (31.81%) 1308 (55.40%)
 Diabetes status < 0.001
  No 2276 (74.48%) 1075 (45.53%)
  Yes 352 (11.52%) 788 (33.38%)
  IGT 210 (6.87%) 194 (8.22%)
  IFG 218 (7.13%) 304 (12.88%)
Anthropometric measurements
 Waist circumference (cm), mean ± SD 89.16 ± 9.84 114.25 ± 13.50 < 0.001
 BMI (kg/m2), mean ± SD 25.13 ± 3.68 35.23 ± 6.55 < 0.001
Biochemical indicators
 GGT (IU/L), median (Q1–Q3) 16.00 (12.00–21.00) 24.00 (18.00–38.00) < 0.001
 Triglycerides (mg/dL), median (Q1–Q3) 78.00 (56.00–108.00) 130.00 (91.00–187.00) < 0.001
 Total cholesterol (mg/dL), mean ± SD 185.00 ± 39.41 194.28 ± 41.41 < 0.001
 HDL cholesterol (mg/dL), mean ± SD 58.13 ± 15.51 46.82 ± 11.87 < 0.001
 AST (u/L), median (Q1–Q3) 21.00 (18.00–25.00) 22.00 (19.00–28.00) < 0.001
 ALT(u/L), median (Q1–Q3) 18.00 (14.00–23.00) 23.00 (17.00–32.00) < 0.001
 Serum folate (nmol/L), median (Q1–Q3) 38.51 (26.27–55.72) 33.98 (24.01–50.06) < 0.001

NAFLD Nonalcoholic Fatty Liver Disease, PIR Poverty Income Ratio, IFG Impaired Fasting Glycemia, IGT Impaired Glucose Tolerance, BMI Body Mass Index, GGT Gamma glutamyl transferase, AST Aspartate Transaminase, ALT Alanine Aminotransferase.