Table 3.
Association of serum folate with NAFLD and AHF.
| Models | NAFLD | AHF | ||
|---|---|---|---|---|
| OR (95% CI) | p-value | OR (95% CI) | p-value | |
| Crude model | ||||
| Tertiles of serum folate | ||||
| Low | Ref | Ref | ||
| Middle | 0.80 (0.70, 0.91) | 0.0009 | 1.01 (0.81, 1.26) | 0.9258 |
| High | 0.69 (0.60, 0.78) | < 0.0001 | 0.97 (0.78, 1.21) | 0.7982 |
| Serum folate, per SD increase | 0.85 (0.81, 0.90) | < 0.0001 | 1.06 (0.97, 1.15) | 0.2294 |
| Adjusted model 1 | ||||
| Tertiles of serum folate | ||||
| Low | Ref | Ref | ||
| Middle | 0.80 (0.70, 0.91) | 0.0011 | 0.86 (0.67, 1.10) | 0.2283 |
| High | 0.65 (0.56, 0.75) | < 0.0001 | 0.50 (0.39, 0.64) | < 0.0001 |
| Serum folate, per SD increase | 0.82 (0.77, 0.87) | < 0.0001 | 0.76 (0.69, 0.84) | < 0.0001 |
| Adjusted model 2 | ||||
| Tertiles of serum folate | ||||
| Low | Ref | Ref | ||
| Middle | 0.84 (0.72, 0.98) | 0.0314 | 0.67 (0.51, 0.88) | 0.0039 |
| High | 0.73 (0.62, 0.86) | 0.0002 | 0.47 (0.35, 0.62) | < 0.0001 |
| Serum folate, per SD increase | 0.85 (0.79, 0.91) | < 0.0001 | 0.77 (0.69, 0.85) | < 0.0001 |
| Adjusted model 3 | ||||
| Tertiles of serum folate | ||||
| Low | Ref | Ref | ||
| Middle | 0.83 (0.71, 0.98) | 0.0254 | 0.66 (0.50, 0.87) | 0.0037 |
| High | 0.73 (0.62, 0.87) | 0.0003 | 0.47 (0.35, 0.63) | < 0.0001 |
| Serum folate, per SD increase | 0.85 (0.79, 0.91) | < 0.0001 | 0.77 (0.69, 0.86) | < 0.0001 |
NAFLD Nonalcoholic fatty liver disease, AHF advanced hepatic fibrosis, PIR poverty income ratio.
Crude model was not adjusted.
Adjusted model 1 adjusted for age, sex, race, education level, PIR.
Adjusted model 2 adjusted for model 1 + total cholesterol, HDL cholesterol, Hypertension status, Diabetes status.
Adjusted model 3 adjusted for model 2 + smoking status, work activities status, recreational activities status, dietary energy intake, dietary protein intake, dietary alcohol intake, dietary folate intake.