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. 2023 Aug 9;3:108. doi: 10.1038/s43856-023-00336-3

Fig. 5. Hypofractionated stereotactic ablative radiotherapy (SART) can induce complete responses in flank xenografts.

Fig. 5

a Nude mouse with bilateral flank 22Rv1 xenografts showing the larger flank tumor immobilized for radiation and centered in a 2 cm radiation field. Image on the right shows treatment response 3 weeks after completing 7.5 Gy x 5 fractions QOD to the left flank. b Growth of PC3 xenografts (n = 4 for shielded and n = 5 for irradiated) treated with 6 Gy x 4 fractions QOD to the larger flank tumor. c Growth of 22Rv1 xenografts (n = 5) treated with 6 Gy x 4 fractions QOD to the larger flank tumor. d Growth of 22Rv1 xenografts (n = 4) treated with 7.5 Gy x 5 fractions QOD to the larger flank tumor. Mean tumor volume ± SD. e Best tumor response by initial tumor size. PR partial response, cCR clinical complete response, pCR pathological complete response.