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. 2023 Aug 9;14:4807. doi: 10.1038/s41467-023-40496-3

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a The fractions of CpG island, promoter and LTR regions marked by H3K9me3 peaks. b The overlap of promoters with de novo H3K9me3, inherited H3K9me3 from CCs, high CpG density and low CpG density at 6 hpa. c The H3K9me3 signal in oocytes, maternal pronuclei of fertilized zygotes, sperm and paternal pronuclei of fertilized zygotes in de novo H3K9me3 regions at 6 hpa. d The H3K9me3 signals in de novo, inherited and erased H3K9me3 regions in control and siSuv39h2 SCNT embryos at 6 hpa. e H3K9me3 signals around CpG-islands in siSuv39h2 and control SCNT embryos at 6 hpa. f H3K9me3 signals around the Wwp2 gene locus in siSuv39h2 and control SCNT embryos at 6 hpa (c). Statistical significance was calculated with a two-tailed Wilcoxon rank-sum test (d). Statistical significance was calculated with a two-tailed Student’s t test. ns, no significance. Source data are provided as a Source Data file.