Table 2. TAT and TTI of EV-based BALF liquid biopsy in comparison with tissue genotyping.

Time	BALF genotyping	Tissue genotyping	P value
TAT (n=120) (day)	1.9±1.1	12.1±7.2	<0.001
TTI (day)			0.01
EGFR-TKI (n=40)	7.8±6.5
Chemotherapy (n=49)	13.8±12.9

Data are shown as mean ± SD. TTI, time with from the date of bronchoscopy or tissue biopsy to the date of treatment initiation (gefitinib or chemotherapy); EV, extracellular vesicles; BALF, bronchoalveolar lavage fluid; TAT, turn-around time; EGFR-TKI, epidermal growth factor receptor-tyrosine kinase inhibitor; SD, standard deviation.