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. 2023 Jul 18;12(7):1477–1495. doi: 10.21037/tlcr-23-14

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2023 Translational Lung Cancer Research. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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Analysis of mutations in the high- and low-risk groups. (A) Overall description of the mutational landscape in TCGA-LUAD patients. (B) Mutational landscape of high-risk patients. (C) Mutational landscape of low-risk patients. (D) Difference analysis of TMB between the high- and low-risk groups. (E) Correlation analysis of TMB and risk score of patients. (F) Joint survival curve of TMB and high- and low-risk groups. SNV, simple nucleotide variation; TMB, tumor mutation burden; TCGA, The Cancer Genome Atlas; LUAD, lung adenocarcinoma.