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. 2023 Jul 19;12(7):1517–1538. doi: 10.21037/tlcr-23-306

Table 2. The Cox regression analysis of clinicopathologic features with the OS in LUAD.

Variable Univariate analysis Multivariate analysis
P value HR 95% CI P value HR 95% CI
Sex (male vs. female) 0.736 0.898 0.482–1.675
Age (≤60 vs. >60 years) 0.228 1.467 0.787–2.735
Pathologic T (T1/T2 vs. T3/T4) 0.616 0.819 0.376–1.785
Pathologic N (N0 vs. N1/N2) 0.005 2.653 1.350–5.216 0.014 2.596 1.214–5.547
Pathologic M (M0 vs. M1) 0.002 2.932 1.465–5.867 0.001 4.987 1.960–12.687
TNM (I/II vs. III/IV) 0.049 1.909 1.002–3.638
Tumor size (≤4 vs. >4 cm) 0.278 0.693 0.357–1.344
Differentiation (1/1–2/2 vs. 2–3/3) 0.038 1.998 1.040–3.842 0.037 2.171 1.049–4.490
Expression (low vs. high) 0.001 4.048 1.760–9.312 0.029 2.822 1.113–7.159

LUAD, lung adenocarcinoma; OS, overall survival; HR, hazard ratio; CI, confidence interval; TNM, Tumor-Node-Metastasis.