Table 2. SUCRA, Probability of Best, and Mean Rank of Different Dosages of Gabapentin and Pregabalin for Patients Undergoing Spinal Surgerya.
| VAS | Opioid consumption | Nausea | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Treatment | SUCRA, % | Probability of best, % | Mean rank | Treatment | SUCRA, % | Probability of best, % | Mean rank | Treatment | SUCRA, % | Probability of best, % | Mean rank |
| Gabapentin 900 mg | 90.8 | 53.3 | 1.8 | Gabapentin 900 mg | 91.0 | 56.1 | 1.7 | Pregabalin 150 mg | 80.0 | 34.3 | 2.6 |
| Gabapentin 1200 mg | 86.6 | 26.1 | 2.2 | Gabapentin 1200 mg | 87.9 | 34.3 | 2.0 | Pregabalin 300 mg | 64.2 | 10.0 | 3.9 |
| Gabapentin 600 mg | 73.3 | 8.5 | 3.4 | Gabapentin 600 mg | 69.3| | 3.9 | 3.5 | Gabapentin 300 mg | 63.6 | 20.9 | 3.9 |
| Gabapentin 300 mg | 57.7 | 3.2 | 4.8 | Pregabalin 300 mg | 63.1 | 3.1 | 4.0 | Gabapentin 600 mg | 63.1 | 10.7 | 4.0 |
| Pregabalin 300 mg | 48.9 | 1.1 | 5.6 | Pregabalin 150 mg | 46.9 | 0.2 | 5.2 | Gabapentin 900 mg | 52.6 | 14.4 | 4.8 |
| Pregabalin 150 mg | 45.4 | 0.0 | 5.9 | Gabapentin 300 mg | 31.2 | 0.2 | 6.5 | Pregabalin 75 mg | 36.0 | 0.9 | 6.1 |
| Gabapentin 400 mg | 34.1 | 3.4 | 6.9 | Pregabalin 75 mg | 25.3 | 0.8 | 7.0 | Gabapentin 800 mg | 35.0 | 7.8 | 6.2 |
| Pregabalin 75 mg | 33.4 | 0.2 | 7.0 | Gabapentin 800 mg | 20.8 | 1.4 | 7.3 | Gabapentin 1200 mg | 30.9 | 1.0 | 6.5 |
| Gabapentin 800 mg | 22.1 | 4.2 | 8.0 | Placebo | 14.5 | 0.0 | 7.8 | Placebo | 24.7 | 0.0 | 7.0 |
| Placebo | 7.7 | 0.0 | 9.3 | NA | NA | NA | NA | NA | NA | NA | NA |
Abbreviations: NA, not applicable; SUCRA, surface under the cumulative ranking curve; VAS, Visual Analog Scale.
The table presents the ranking for 3 different outcomes: VAS for pain intensity, opioid consumption, and nausea. The SUCRA values, presented as percentages, represent the probabilities of each treatment being the best treatment or one of the top-ranked treatments for the corresponding outcome. A higher SUCRA value indicates a higher likelihood that a treatment is among the top-ranked options. The probability of best values provide the probability of each treatment being the best treatment for the specific outcome. The closer the SUCRA and probability of best values are to 100%, the higher the probability that a therapy is the best treatment or one of the top-ranked treatments. The mean ranks indicate the relative effectiveness of each treatment option for each outcome, with lower ranks indicating better performance. The table provides a comprehensive overview of the comparative effectiveness of different dosages of gabapentin and pregabalin for pain control, opioid consumption, and nausea in patients undergoing spinal surgery.