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. 2023 Jul 27;14:1241038. doi: 10.3389/fimmu.2023.1241038

Figure 1.

Figure 1

The durability of cross-reactive anti-RBD antibody responses upon natural infection is impacted by disease severity. Anti-RBD antibody titers against the Wuhan, Gamma, Mu, and Delta variants, in naturally-infected individuals who developed mild (A, B) or severe disease (C). Each circle represents an individual sample. The height of the bars and the numbers over them indicate the geometric mean titer. The 95% CI is also shown. The Wilcoxon test was performed. The dotted line represents the limit of detection of the assay. In (A), the Javeriana cohort is shown (n=12). In (B), the Andes cohort is shown (1-month n=26 and 6-month PSO n=21). In (C), the El Rosario cohort is shown (n=13). ns, Not statistically significant. *p-value <0.05; **p-value <0.01; ***p-value <0.001.