Table 1.
Characteristics of the studies included in the current meta-analysis.
| References | Sample | Sex (M/F) | Age (year) | Duration (year) | CAG Repeats | ICARS | SARA | Software | Threshold |
|---|---|---|---|---|---|---|---|---|---|
| Lukas et al. (14) | SCA3 9 | 4/5 | 53 ± 9.8 | NA | 64 (58–73) | 30 ± 12.4 | NA | SPM2 | p < 0.001 corrected |
| HC 15 | 9/6 | 60 ± 10 | |||||||
| Goel et al. (7) | SCA3 10 | 5/5 | 38.0 ± 12.6 | 5.8 ± 4.9 | NA | 48.6 ± 36.0 | NA | SPM2 | p < 0.05 corrected |
| HC 10 | 5/5 | NA | |||||||
| D'Abreu et al. (5) | SCA3 45 | 30/15 | 47.02 ± 12.23 | 9.97 ± 6.13 | 72 (65–81) | 36.36 ± 18.5 | NA | SPM2 | p < 0.05 corrected |
| HC 51 | NA | 44.08 ± 11.78 | |||||||
| Guimaraes et al. (8) | SCA3 38 | 21/17 | 52.76 ± 12.70 | 9.3 ± 2.7 | 68.08 ± 4.5 | 32.08 ± 14.01 | 14.65 ± 7.33 | SPM8 | p < 0.05 corrected |
| HC 38 | 20/18 | 48.86 ± 12.07 | |||||||
| Hernandez-Castillo et al. (10) | SCA3 17 | 7/10 | 40.1 ± 11.9 | 6.9 ± 4.4 | NA | NA | 13.26 ± 7.23 | FSL | p < 0.05 corrected |
| HC 17 | 7/10 | NA | |||||||
| Meles et al. (15) | SCA3 17 | 9/8 | 35.6 ± 10.2 | 9.7 ± 7 | 70 (65.5–72.5) | NA | 10 (3.5–15.5) | SPM12 | p < 0.05 corrected |
| HC 16 | 8/8 | NA | |||||||
| Gitai et al. (6) | SCA3 24 | 12/12 | 46.1 ± 14.7 | 8.8 ± 5.2 | 71.8 ± 4.5 (63–80) | NA | 16 ± 6.6 | SPSSv15.0 | p < 0.05 corrected |
| HC 18 | 6/12 | 45.9 ± 16.6 |