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. 2023 Jul 12;299(8):105038. doi: 10.1016/j.jbc.2023.105038

Figure 1.

Figure 1

Tyrosine modifications.A, tyrosine modifications targeting the hydroxyl group of the phenolic ring are sulfation, phosphorylation, and AMPylation (referred to as adenylation). Tyrosine nitration and halogenation (addition of chloride/bromide onto the ortho carbon) are the newest entries in the biological repertoire of tyrosine PTMs. B, biological pathways and chemistry that contributes to tyrosine nitration. PTMs, posttranslational modifications.