. Author manuscript; available in PMC: 2023 Aug 10.

Published in final edited form as: J Nephrol. 2015 Mar 10;28(6):739–747. doi: 10.1007/s40620-015-0188-y

Table 3.

Univariate and multivariate predictors of physical performance in ISWT and leg strength

ISWT	Univariate model		Multivariable model 1		Multivariable model 2
			Adjusted R² = 0.203, p<0.001		Adjusted R² = 0.338, p<0.001
	β	p	β	p	β	p
LVDD	−0.303	0.007^*	−0.307	0.004^*	−0.187	0.116
Age	−0.359	0.001^*	−0.361	0.001^*	−0.335	0.001^*
BMI	−0.254	0.025^*	−0.226	0.051	0.023	0.850
WBLM%	0.435	<0.001^*			0.328	0.001^*
Diabetes	−0.369	<0.001^*			−0.290	0.004^*
Leg strength	Univariate model		Multivariable model 3		Multivariable model 4
			Adjusted R² = 0.044, p = 0.039		Adjusted R² = 0.098, p = 0.004
	β	p	β	p	β	p
LVDD	−0.238	0.039^*	−0.238	0.039^*	−0.159	0.179
Age	−0.180	0.119	−0.194	0.087	−0.152	0.174
BMI	−0.108	0.355	−0.047	0.694	0.240	0.135
WBLM%	0.332	0.004^*			0.332	0.004^*
Diabetes	−0.008	0.944			−0.084	0.469

The relationship between LVDD presence and ISWT and leg strength performance and potential confounders (age, BMI, WBLM, diabetes status) of these associations were tested in univariate regression analysis. Multivariable Models 1 and 3 tested multivariable prediction of LVDD, age and BMI on ISWT and leg strength, respectively. Multivariable Models 2 and 4 added WBLM and diabetes status into Models 1 and 3 ISWT incremental shuttle walk test, LVDD left ventricular diastolic dysfunction, BMI body mass index, WBLM whole body lean mass

Statistical significance between groups