FIGURE 4.

Extensive phenotypic pleiotropy is present in mouse models for pigmentation genes. The 296 genes annotated in MGI with the mammalian phenotype (MP) term “pigmentation phenotype” were evaluated for additional MP terms, and the graph illustrates the percentage of these 296 genes with additional annotations. Clinical relevance of these pigmentation genes is indicated by the most commonly occurring high-level phenotype annotations: integument, growth/size/body region, mortality/aging, nervous system, and vision/eye