Table 3.

Prognostic correlation between serum biomarkers measured at their maximum peak of blood release (D7 for sNfL, D1 for sGFAP) and patients’ outcome evaluated through clinical and rehabilitation scales scored at M1 and M3 after stroke.

Clinical/rehabilitation scale		sNfL-D7		sGFAP-D1
		Spearman’s rho	p-value	Spearman’s rho	p-value
NIHSS	M1	0.67	0.0004	0.75	<0.0001
	M3	0.63	0.003	0.63	0.001
mRS	M1	0.51	0.01	0.53	0.005
	M3	0.35	0.14	0.24	0.29
Norm. mRS	M1	0.24	0.25	0.39	0.04
	M3	0.17	0.49	0.17	0.44
TCT	M1	−0.51	0.01	−0.62	0.0007
	M3	−0.50	0.03	−0.37	0.10
FAC	M1	−0.48	0.02	−0.63	0.0005
	M3	−0.60	0.01	−0.57	0.007
Total FIM	M1	−0.67	0.0003	−0.75	<0.0001
	M3	−0.65	0.003	−0.55	0.01
Motor FIM	M1	−0.62	0.001	−0.72	<0.0001
	M3	−0.56	0.01	−0.42	0.05
Cognitive FIM	M1	−0.73	5.9 × 10−5	−0.73	<0.0001
	M3	−0.56	0.01	−0.64	0.002