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. 2023 Jul 16;14(12):2289–2300. doi: 10.7150/jca.85906

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Silencing of GINS1 weakens DOX resistance in lymphoma cells. A. GINS1 protein in parental and DOX-resistant FARAGE and SU-DHL-2 cells examined by western blot analysis. B-C. FARAG/DOX and SU-DHL-2/DOX cells were infected with sh-GINS1 or oe-GINS1 expressing lentiviral particle, protein levels of GINS1 and Ki67 in FARAG/DOX and SU-DHL-2/DOX cells after lentiviral particle infection were examined by western blot analysis. D. Cell viability of FARAG/DOX and SU-DHL-2/DOX under different doses of DOX treatment was evaluated by CCK-8. E. Colony formation ability of FARAG/DOX and SU-DHL-2/DOX cells under 0.5μM DOX treatment examined by colony formation assay. Data represent mean values ± SEM of three independent experiments. *, P < 0.05.