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. 2023 Aug 9;2(1):e000407. doi: 10.1136/bmjmed-2022-000407

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© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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Comparison of the numbers needed to treat between landmark mechanical thrombectomy trials and other interventions. The figure shows the numbers needed to treat of the AURORA and HERMES meta-analyses and their respective randomised controlled trials (HERMES: MR CLEAN, ESCAPE, EXTEND-IA, REVASCAT, and SWIFT-PRIME; AURORA: DEFUSE-3 and DAWN^{1 3–10}), which looked at achieving functional independence at 90 days. In the TAVI PARTNER trial, the number needed to treat looked at preventing death within five years.¹³ In the trials on primary percutaneous coronary intervention (pPCI), the number needed to treat was to prevent short term mortality and short term recurrence.¹² For statins, the number needed to treat was to prevent one stroke¹¹