Table 1.
Schedule of the study process
| Time point | Study period | |||||||
| Enrolment | Allocation | Post-allocation | ||||||
| Precycle | IVF/ICSI-ET | Follow-up | ||||||
| Days 2–4 in Follicular phase | Day 7 after ovulation | MC day 1–3 | Trigger day | OPU | Embryo transfer | 14 days after embryo transfer | 12 weeks after embryo transfer | |
| Enrolment | ||||||||
| Eligibility screen | √ | √ | ||||||
| Informed consent | √ | |||||||
| Randomisation | √ | |||||||
| Allocation | √ | |||||||
| Interventions | ||||||||
| Oestrogen pretreatment |
|
|||||||
| GnRH-ant protocol |
|
|||||||
| Luteal support |
|
|||||||
| Assessments | ||||||||
| Baseline data | √ | |||||||
| Primary Outcome | √ | |||||||
| Secondary outcome | √ | √ | √ | √ | √ | |||
Precycle, the oestrogen-priming menstrual cycle preceding the IVF/ICSI-ET.
GnRH-ant, gonadotrophin releasing hormone antagonist; IVF/ICSI-ET, in vitro fertilisation/intracytoplasmic sperm injection-embryo transfer; MC, menstrual cycle; OPU, oocyte pick-up.