Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Jul 27;14:1220426. doi: 10.3389/fendo.2023.1220426

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2023 Yang, Liu, Jiang, Liu, Luo, Li, Zhao, Han, Chen, Li, Xiao and Sun

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Regulatory mechanism of FGF21 expression. The mRNA expression of FGF21 was upregulated by some transcription factors (PPARα, PPARγ, ATF4, RORα, RA, CREBH, TRs and Nur77) and inhibited by Nrf2. PPARα, peroxisome proliferator-activated receptor α; ATF4, activating transcription factor 4; RORα, retinoic acid receptor-associated receptor α; CREBH, cyclic adenosine monophosphate-responsive element-binding protein H; Nrf2, Nuclear factor erythroid 2-related factor 2; PPREs, PPARα response elements.