Table 2.

Laboratory and ECG Monitoring.

Labs	Baseline	Supratherapeutic concentration	N at baseline and supratherapeutic concentration
Potassium (mmol/L), median [IQR]	4.3 [3.9–4.5]	4.0 [3.6–4.6]	76, 85
Bicarbonate (mmol/L), median [IQR]	23 [22–26]	25 [23–27]	59, 69
ALT (U/L), median [IQR]	22 [16–36]	31 [20–44]	82, 86
AST (U/L), median [IQR]	23 [19–37]	29 [22–43]	79, 82
Total bilirubin (mg/dL), median [IQR]	0.4 [0.2–0.5]	0.5 [0.3–0.6]	79, 78
Alk phos (U/L), median [IQR]	87 [70–121]	90 [74–130	80, 84
QTc (ms), median [IQR]	442 [427–463]	456 [435–479]	47, 48

ECG, electrocardiogram; IQR, interquartile range; ALT, alanine aminotransferase; AST, aspartate aminotransferase; Alk Phos, alkaline phosphatase; QTc, corrected QT interval.