FIG 2.

Discriminatory performance after adjustment for age of the image-based risk model and the Tyrer-Cuzick v8 risk model at study entry stratified by mode of detection, estrogen receptor status, and tumor invasiveness. Multiple estimations were performed for breast cancers diagnosed within 10 years after study entry. The horizontal line denotes the aAUC point estimate (0.65) of the image-based risk model for 10-year follow-up in the full study sample. The aAUCs for the image-based model were significantly higher after 10 years of follow-up for screen detected, symptomatic, ER-positive, and invasive breast cancers, P < .01. aAUC, AUC after adjustment for age; ER, estrogen receptor.