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. Author manuscript; available in PMC: 2024 Jun 1.
Published in final edited form as: Gynecol Oncol. 2023 May 4;173:130–137. doi: 10.1016/j.ygyno.2023.03.018

Table 3.

Reported chemotherapy toxicities for Carboplatin + Paclitaxel x8C subgroup, by age.

Toxicity Category Age < 70
(%)
Age ≥ 70
(%)
P
Leukopenia (≥G3) 52.9 53.9 0.84
Thrombocytopenia (≥G3) 24.4 25.2 0.86
Neutropenia (≥G4) 62.2 67.8 0.25
Anemia (≥G3) 12.1 12.2 0.97
GI (≥G3) 9.5 13.9 0.15
GU/renal (≥G2) 5.8 4.3 0.54
Peripheral neuropathy (≥G2) 19.7 35.7 <0.001
Pain (≥G3) 5.5 4.3 0.63
Pulmonary (≥G3) 2.4 2.6 0.90
Hepatic (≥G2) 4.7 4.3 0.89
Infection (≥G3) 8.8 11.3 0.40
Auditory (≥G2) 2.7 3.5 0.66

GI: gastrointestinal.

GU: genitourinary.

Chemotherapy toxicity rates were computed by age group and the rates were compared using Pearson’s Chi-squared test.