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. 2023 Jul 27;13:1210125. doi: 10.3389/fonc.2023.1210125

Table 3.

The results of the univariate and multivariate Cox regression analysis.

Variable PFS OS
Log Rank Cox Regression Log Rank Cox Regression
x2 p HR (95%CI) p x2 p HR (95%CI) p
Age (years) 5.879 0.015* 3.532(1.301-9.593) 0.013 9.696 0.002* 5.644(1.430-22.277) 0.013
Menopausal Status 4.524 0.033* 4.644 0.031*
Tumor Location 0.233 0.629 0.078 0.780
Histologic Type 2.992 0.084 2.16 0.142
Clinical Stage 16.067 <0.001* 19.806 <0.001*
Clinical T Stage 1.273 0.736 6.472 0.091
Clinical N Stage 9.238 0.010* 16.255 <0.001*
Clinical M Stage 15.472 <0.001* 2.977(1.217-7.283) 0.017 19.46 <0.001* 3.499(0.962-12.727) 0.057
ER Status 3.902 0.048* 3.678 0.055
PR Status 5.084 0.024* 5.357 0.021*
HER2 Status 0.027 0.870 0.035 0.853
Molecular Subtype 4.626 0.201 4.763 0.190
Ki-67 4.174 0.041* 1.157 0.282
Treatment 5.994 0.050 4.931 0.085
SUVmax 7.058 0.008* 2.028 0.154
SUVmin 5.359 0.021* 4.240(1.814-9.910) 0.001 2.598 0.107
SUVmean 3.950 0.047* 1.686 0.194
SUVpeak 6.130 0.013* 1.685 0.194
MTV 1.772 0.183 3.848 0.050
TLG 2.891 0.089 3.758 0.053
Rad-score 4.261 0.039* 2.660(1.029-6.880) 0.044 6.930 0.008* 3.627(1.171-11.241) 0.026

The clinicopathological factors and Rad-score were analyzed by the log-rank method in univariate analysis, and then characteristics with p < 0.05 were taken into the multivariate Cox regression to construct the final model. HR, hazard ratio; CI, confidence interval; ER, estrogen receptor; PR, progesterone receptor; HER2, human epidermal growth factor receptor 2; SUV, standardized uptake value; MTV, metabolic tumor volume; TLG, total lesion glycolysis; Rad-score, radiomic score. *P < 0.05.