Table 3.
The results of the univariate and multivariate Cox regression analysis.
Variable | PFS | OS | ||||||
---|---|---|---|---|---|---|---|---|
Log Rank | Cox Regression | Log Rank | Cox Regression | |||||
x2 | p | HR (95%CI) | p | x2 | p | HR (95%CI) | p | |
Age (years) | 5.879 | 0.015* | 3.532(1.301-9.593) | 0.013 | 9.696 | 0.002* | 5.644(1.430-22.277) | 0.013 |
Menopausal Status | 4.524 | 0.033* | 4.644 | 0.031* | ||||
Tumor Location | 0.233 | 0.629 | 0.078 | 0.780 | ||||
Histologic Type | 2.992 | 0.084 | 2.16 | 0.142 | ||||
Clinical Stage | 16.067 | <0.001* | 19.806 | <0.001* | ||||
Clinical T Stage | 1.273 | 0.736 | 6.472 | 0.091 | ||||
Clinical N Stage | 9.238 | 0.010* | 16.255 | <0.001* | ||||
Clinical M Stage | 15.472 | <0.001* | 2.977(1.217-7.283) | 0.017 | 19.46 | <0.001* | 3.499(0.962-12.727) | 0.057 |
ER Status | 3.902 | 0.048* | 3.678 | 0.055 | ||||
PR Status | 5.084 | 0.024* | 5.357 | 0.021* | ||||
HER2 Status | 0.027 | 0.870 | 0.035 | 0.853 | ||||
Molecular Subtype | 4.626 | 0.201 | 4.763 | 0.190 | ||||
Ki-67 | 4.174 | 0.041* | 1.157 | 0.282 | ||||
Treatment | 5.994 | 0.050 | 4.931 | 0.085 | ||||
SUVmax | 7.058 | 0.008* | 2.028 | 0.154 | ||||
SUVmin | 5.359 | 0.021* | 4.240(1.814-9.910) | 0.001 | 2.598 | 0.107 | ||
SUVmean | 3.950 | 0.047* | 1.686 | 0.194 | ||||
SUVpeak | 6.130 | 0.013* | 1.685 | 0.194 | ||||
MTV | 1.772 | 0.183 | 3.848 | 0.050 | ||||
TLG | 2.891 | 0.089 | 3.758 | 0.053 | ||||
Rad-score | 4.261 | 0.039* | 2.660(1.029-6.880) | 0.044 | 6.930 | 0.008* | 3.627(1.171-11.241) | 0.026 |
The clinicopathological factors and Rad-score were analyzed by the log-rank method in univariate analysis, and then characteristics with p < 0.05 were taken into the multivariate Cox regression to construct the final model. HR, hazard ratio; CI, confidence interval; ER, estrogen receptor; PR, progesterone receptor; HER2, human epidermal growth factor receptor 2; SUV, standardized uptake value; MTV, metabolic tumor volume; TLG, total lesion glycolysis; Rad-score, radiomic score. *P < 0.05.