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. 2023 Jun 19;51(14):7269–7287. doi: 10.1093/nar/gkad523

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© The Author(s) 2023. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — Chromatin profiling of HOXA and HOXC genes in SMCHD1-deficient cells. (A) Profiling of the HOXA gene locus (chr7:27090339–27211142, 120 803 bp) in controls (black) or FSHD2 (red) MFs for H3K27Ac, H3K27me3 or CTCF enrichment. (B) Profiling of the HOXA gene locus (chr7:27090339–27211142, 120 803 bp) in controls (black) or BAMS (cyan) NCSCs for H3K27Ac, H3K27me3 or CTCF enrichment. (C) Profiling of the HOXC gene locus (chr12:53930562–54058000; 127 438 bp) in controls (black) or FSHD2 (red) MFs for H3K27Ac, H3K27me3 or CTCF enrichment. (D) Profiling of the HOXC gene locus (chr12:53930562–54058000; 127 438 bp) in controls (black) or BAMS (cyan) NCSCs for H3K27Ac, H3K27me3 or CTCF enrichment.