Table 2.

Diagnostic Subtypes of ALPS^a

Diagnosis	Definition
ALPS-FAS	Meets clinical criteria for ALPS plus germline FAS mutation
ALPS-sFAS	Meets clinical criteria for ALPS plus somatic FAS mutation
ALPS-FASL	Meets clinical criteria for ALPS plus germline FASL mutation
ALPS-CASP10	Meets clinical criteria for ALPS plus germline CASP10 mutation
ALPS-U	Meets clinical criteria for ALPS but no detected genetic lesion

Abbreviations: ALPS, autoimmune lymphoproliferative syndrome; FAS, first apoptosis signal receptor; FASL, first apoptosis signal receptor ligand; CASP10, caspase 10.

^aAccording to the revised 2010 criteria.