Table 4.

Characteristics of individuals with parallel IgG EIA results indicating HEV-C1 exposure.

Patient	Age	Sex	Ethnicity	Underlying conditions	HEV-C1 p241 OD value	A/C ratio∗	Documented unexplained hepatitis
1	30	M	Chinese	Renal transplant	1.531	N/A	No
2	59	M	Chinese	Renal transplant	2.225	N/A	No
3	50	M	South Asian	Liver transplant	1.338	1.433	No
4	70	M	Chinese	Heart transplant	2.711	1.063	Yes
5	75	M	Chinese	Liver transplant	0.967	0.478	Yes
6	40	F	Chinese	Liver transplant	1.928	1.585	No
7	73	M	Chinese	Heart transplant	1.290	1.290	Yes
8	62	M	Chinese	Diabetes, HBV carrier	0.988	1.278	No
9	70	F	Chinese	Diabetes, HBV carrier	1.719	1.426	Yes†
10	74	M	Chinese	Hypertension	1.500	1.183	Yes
11	61	M	Chinese	HBV carrier	0.925	0.692	No

EIA, enzymatic immunoassay; HBV, hepatitis B virus; HEV-C1, Rocahepevirus ratti; N/A, not applicable; OD, optical density.

^∗A/C ratio = OD_{HEV-A4 p239}/OD_{HEV-C1 p241} only applied when samples are positive in both EIAs.

^†Transient alanine aminotransferase elevation when HBV was suppressed with entecavir.