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. 2023 Jun 20;22(8):100603. doi: 10.1016/j.mcpro.2023.100603

Fig. 6.

Fig. 6

Potential plasma and urine biomarkers for ccRCC.A and B, the top 20 proteins with the lowest FDR values in plasma (A) and urine (B). C and D, the top 20 proteins with the highest mean decrease accuracy value of random forest model in plasma and urine. E and F, ROC curve of plasma panel (E) and urine panel (F) for the diagnostic model for ccRCC. G, discriminant results heat map of plasma FGFR1, GOT1, FGFBP2, the plasma panel, urine CETP, SEZ6L2, COX5B, and the urine panel for ccRCC and HC samples using the cutoff value with a specificity of 95%. Red: positive with a specificity of 95%. ccRCC, clear cell renal cell carcinoma; FDR, false discovery rate; HC, healthy controls.