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. 2023 Jun 20;22(8):100603. doi: 10.1016/j.mcpro.2023.100603

Table 1.

Enriched pathway and function in plasma and urine

Function Enriched pathway in plasma Enriched pathway in urine
Common with tissue Plasma only Common with tissue Urine only
Cellular growth and development Actin cytoskeleton signaling Actin cytoskeleton signaling
Axonal guidance signaling CDC42 signaling
Germ cell-sertoli cell junction signaling Th2 pathway
Integrin signaling
Remodeling of epithelial adherens junctions
Immune response Phagosome formation Epithelial adherens junction signaling Phagosome formation Clathrin-mediated endocytosis signaling
B cell receptor signaling Neuroinflammation signaling pathway Granulocyte adhesion and diapedesis
IL-15 signaling Leukocyte extravasation signaling
Systemic lupus erythematosus in B cell signaling pathway Agranulocyte adhesion and diapedesis
Intracellular and second messenger signaling RHOA signaling RHOGDI signaling
Actin nucleation by ARP-WASP complex Signaling by Rho family GTPases
RAC signaling Glucocorticoid receptor signaling
Calcium signaling