Table. Summary of Survival in the 5-Year Final Analysis.
No. of events (%) | KM estimate, mo | Treatment difference KM estimate, % (80% CI)c | Overall unstratified HR (80% CI)d | |||
---|---|---|---|---|---|---|
Group 1 (n = 76)a | Group 2 (n = 74)b | Group 1a | Group 2b | |||
LRFS | 53 (69.7) | 56 (75.7) | 28.02 | 21.12 | 6.90 (−2.60 to 16.40) | 0.82 (0.64 to 1.06) |
RRFS | 50 (65.8) | 54 (73.0) | 32.91 | 24.69 | 8.22 (−1.58 to 18.01) | 0.81 (0.62 to 1.05) |
DMFS | 54 (71.1) | 61 (82.4) | 27.62 | 14.99 | 12.63 (3.79 to 21.48) | 0.73 (0.57 to 0.94) |
Abbreviations: DMFS, distant metastasis–free survival; HR, hazard ratio; KM, Kaplan-Meier; LRFS, local recurrence-free survival; RRFS, regional recurrence-free survival.
Talimogene laherparepvec plus surgery.
Surgery alone.
Group 1 – group 2.
Group 1 / group 2.